Modifying Enzymes
Cayman Chemical Decnoyl-Coenzyme Ahydrate 5mg
A thioester of decanoic acid and CoA; inhibits the activity of mitochondrial CS and GDH isolated from rat brain (IC50s = 437 and 420 µM, respectively); inhibits FadR from binding its promoter in E. coli (Ki = 2 µM); produced during isomerase-dependent β-oxidation of oleic acid in isolated rat heart mitochondria
Carnabio Usa Inc BTN - IRAK4 / 10UG
BTN-IRAK4, Full-length, Wild type, Amino Acid 1-460(end), NP_057207.2, 55 kDa, Insect (sf21); 10microg
Cayman Chemical Decnoyl-Coenzyme Ahydrate 10mg
A thioester of decanoic acid and CoA; inhibits the activity of mitochondrial CS and GDH isolated from rat brain (IC50s = 437 and 420 µM, respectively); inhibits FadR from binding its promoter in E. coli (Ki = 2 µM); produced during isomerase-dependent β-oxidation of oleic acid in isolated rat heart mitochondria
Cayman Chemical N-Oleoyl LeucIn 10mg
An N-acyl amide that uncouples mitochondrial respiration independent of UCP1 in vitro; decreases body weight and food intake, preferentially decreasing fat mass in a diet-induced obesity mouse model; improves glucose homeostasis and increases energy expenditure while slightly decreasing overall locomotor activity
Abcam URB754, Monoacylglycerol lipase inhibitor, 10MG
MW 266.3 g/mol, Purity >98%. Reported potent and non-competitive monoacylglycerol lipase (MAGL) inhibitor (IC₅₀ = 200 nM). Inhibits FAAH (IC₅₀ = 32 μM) and binds weakly to the rat CB₁ receptor (IC₅₀ = 3.8 μM). Shows vasodilatory activity.
The product is subject to the following: Abcam Restricted Use Statement
Carnabio Usa Inc BTN - FGFR3 / 10UG
BTN-FGFR3, Cytoplasmic domain, Wild type, Amino Acid 436-806(end), NP_000133.1, 52 kDa, Insect (sf21); 10microg
Cayman Chemical EthylmaLNyl Coenzyme AsodI
An intermediate in the ethylmalonyl-CoA pathway in bacteria
Sigma Aldrich Fine Chemicals Biosciences beta-Galactosidase from bovine liver Grade III, lyophilized powder, >=0.15 units/mg protein | 9031-11-2 | MFCD00130623 | 10UN
beta-Galactosidase from bovine liver Grade III, lyophilized powder, >=0.15 units/mg protein | 9031-11-2 | MFCD00130623 | 10UN
Medchemexpress LLC HY-110115 5mg Medchemexpress, TC-Mps1-12 CAS:1206170-62-8 Purity:>98%
Medchemexpress, HY-110115 5mg TC-Mps1-12 CAS:1206170-62-8 TC-Mps1-12 is a potent and selective monopolar spindle 1 (Mps1) inhibitor, with an IC50 of 6.4 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
ABclonal Technology Endonuclease VIII
Endonuclease VIII originates from E.coli and possesses both N-glycosylase and AP-endonuclease activity. The N-glycosylase activity releases damaged pyrimidines from double-stranded DNA, generating an apurinic (AP site). The AP-endonuclease the phosphodiester bond at the AP site, forming 3’-P and 5’-P ends. Damaged bases recognized and removed by Endonuclease VIII include: urea, 5, 6-dihydroxythymine, thymine glycol, 5-hydroxy-5-methylhyd antoin, uracil glycol, 6-hydroxy-5, 6-dihydrothymine and methylhydroxy- methyluracil.
Sigma Aldrich Fine Chemicals Biosciences n Heptanoyl coenzyme A lit5MG
n Heptanoyl coenzyme A lit5MG
Cayman Chemical Lysosomal ACD LIpase ActIvIt
Cayman's LAL Activity MaxSpec Assay Kit includes the necessary reagents to quantify lysosomal acid lipase (LAL) activity in dried blood spots. The LAL Activity MaxSpec Assay Substrate (P-PMHC) has been designed to function as a highly selective substrate for LAL, which hydrolyzes the fatty acyl group of P-PMHC resulting in the formation of the LAL Activity MaxSpec Assay Product 4-propyl-8-methyl-7-hydroxycoumarin (PMHC). Using the LAL Activity MaxSpec Assay Kit, LAL activity may be quantified directly by fluorometry or by LC-MS in combination with the LAL Activity MaxSpec Assay Internal Standard.
Carnabio Usa Inc MARK2/10UG/FULL-LENGTH
MARK2, Full-length, Wild type, Amino Acid 1-745, NP_059672.2, Expressed in Insect (sf21); 10microg
Medchemexpress LLC HY-19801 5mg Medchemexpress, CVT-10216 CAS:1005334-57-5 Purity:>98%
Medchemexpress, HY-19801 5mg CVT-10216 CAS:1005334-57-5 CVT-10216 is a highly selective, reversible aldehyde dehydrogenase-2 (ALDH-2) inhibitor with an IC50 of 29 nM. CVT-10216 also has inhibitory effect of ALDH-1 with an IC50 of 1.3 μM. CVT-10216 can reduce excessive alcohol drinking in alcohol-preferring rats and exhibit anxiolytic effects. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.